DMT-2'-F-dG(iBu)-CE Phosphoramidite Application_Other Raw material "Activation of UTP-sensitive P2Y2 receptor

"Activation of UTP-sensitive P2Y2 receptor induces the expression of cholinergic genes in cultured cortical neurons: a signaling cascade triggered by Ca2+ mobilization and extracellular regulated kinase phosphorylation

modified uridine nucleotide supplied for enzymatic incorporation into RNA during IVT using RNA polymerases such as T7 RNA polymerase

Compatible with standard phosphoramidite chemistry and most commercial DNA synthesizers

Pinky SC Lee

and Drew Weissman

DMT-2'-F-dG(iBu)-CE Phosphoramidite Application_Other Raw material "Activation of UTP-sensitive P2Y2 receptorDMT 2 F dG(iBu) CE Phosphoramidite is a 2' fluoro (2' F) phosphoramidite monomer used for solid phase oligonucleotide synthesis. It contains a 2' F modification on the sugar of deoxyguanosine (dG) with isobutyryl (iBu) base protection, a 5 dimethoxytrityl (DMT) group for 5' hydroxyl protection, and a cyanoethyl (CE) protecting group on phosphite. Synthesis of RNA oligonucleotides using 2' F phosphoramidite increases the nuclease resistance and binding