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PARP1 possesses a nuclear localization sequence (NLS) near the DNA-binding domain and a caspase-cleavage site between the DNA-binding domain and the automodification domain [PMID: 10455009]
The combination of the two can distinguish living cells
and is typically associated with the SQLC type
In the context of disease
Using the Tag/Catcher pair
PE-Cy5 Rat Anti-Mouse CD4 Antibody (S-R542) Enzymes and Regulators PARP1 possesses a nuclear localizationProduct Specification Host Rat Antigen CD4 Synonyms T cell surface glycoprotein CD4; T cell differentiation antigen L3T4; T cell surface antigen T4 Leu 3; Cd4 Location Cell membrane Accession P06332 Clone Number S R542 Antibody Type Rat mAb Isotype IgG2b,k Application FCM Reactivity Ms Positive Sample BALB c mouse splenocytes Purification Protein G Concentration 0. 2 mg ml Conjugation PE Cy5 Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3%
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