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2-(dibromopyridazinediones-N-methyl-N'-Propanamido-PEG2-amido)-1,3-bis(endo-BCN-PEG2-amido-ethoxy)propane VB-4145 Construction of an immunotoxin via

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Description

Construction of an immunotoxin via site-specific conjugation of anti-Her2 IgG and engineered Pseudomonas exotoxin A

202314143 Keywords: Traceless Release

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2-(dibromopyridazinediones-N-methyl-N'-Propanamido-PEG2-amido)-1,3-bis(endo-BCN-PEG2-amido-ethoxy)propane VB-4145 Construction of an immunotoxin viaReferences: Lee, M. T. W.; et al. Enabling the controlled assembly of antibody conjugates with a loading of two modules without antibody engineering Chem. Sci. (2017), 8, 2056 2060 DOI: 10. 1039 C6SC03655D Keywords: Antibody Conjugates; Dibromopyridazinedione; BCN

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