Secreted predominantly by monocytes/macrophages and dendritic cells—especially M2 tumor-associated macrophages—CCL18 acts as a chemoattractant for lymphocytes and immature dendritic cells while also functioning as a neutral CCR3 antagonist and binding promiscuously to PITPNM3
CD95 (APO-1/Fas) is an important inducer of the extrinsic apoptosis signaling pathway and therapy induced apoptosis of many tumor cells has been linked to the activity of CD95
It also promotes the growth of rat synoviocytes
thereby triggering a vicious cycle and exacerbating disease
Vascular endothelial growth factor (VEGF) is a signal protein produced by many cells that stimulates the formation of blood vessels
PDE4D7 GST Tag Protein, Human Tag & Loading Control Antibody Secreted predominantly by monocytes/macrophages andProduct Specification Species Human Synonyms 3',5' cyclic AMP phosphodiesterase 4D,DPDE3 Accession Q08499 11 Amino Acid Sequence K2 T748(end); N terminal GST tag 3C Expression System Baculovirus InsectCells Molecular Weight 111. 4 kDa Purity >80% by SDS PAGE Conjugation Unconjugated Tag GST Tag Physical Appearance Liquid Storage Buffer 50 mM Tris, 150 mM NaCl, 1 mM DTT, 10% glycerol, pH7. 5 Stability & Storage Stable for 12 months upon stored at 80