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The binding of PD-L1 to the inhibitory checkpoint molecule PD-1 transmits an inhibitory signal based on interaction with phosphatases (SHP-1 or SHP-2) via Immunoreceptor Tyrosine-Based Switch Motif (ITSM)
it is also referred to as ATAR (another TRAF-associated receptor)
LEU3 Accession P01730 Amino Acid Sequence Lys26-Trp390
Analogous to other rGCs
depending on the context of the disease
Her2 Fc Chimera Protein, Human Size:100μg The binding of PD-L1 toProduct Specification Species Human Synonyms Her2, ERBB2, CD340, HER 2 neu, MLN19, NEU, NG, TKR1 Accession P04626 1 Amino Acid Sequence Thr23 Thr652, with C hIgG1 Fc Expression System HEK293 Molecular Weight 110 120kDa Purity >95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag Human Fc Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4 Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure water
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