thus indicating that MICA/B shedding is a therapeutic target in immune-oncology
modulating lymphocyte function
whose proteasomal degradation activates the cGAS-STING pathway to enhance anti-tumor immunity
68-300ng/mL Applications Serum
Species Human Accession P22301 Amino Acid Sequence SENSCTHFPGNLPNMLRDLRDAFSRVKTFFQMKDQLDNLLLKESLLEDFKGYLGCQALSEMIQFYLEEVMPQAENQDPDIKAHVNSLGENLKTLRLRLRRCHRFLPCENKSKAVEQVKNAFNKLQEKGIYKAMSEFDIFINYIEAYMTMKIRNGGGGSHHHHHHHHHH
Sialoadhesin/CD169 Recombinant Rabbit mAb, PBS Only (SDT-3228-8) IHC Pathology Antibody thus indicating that MICA/B sheddingProduct Specification Host Rabbit Antigen CD169 Synonyms Sialoadhesin; Sheep erythrocyte receptor (SER); Sialic acid binding Ig like lectin 1 (Siglec 1); Sa; Sn; Siglec1 Immunogen Recombinant Protein Location Cell membrane Accession Q62230 Clone Number SDT 3228 8 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, ICC Reactivity Hu, Ms, Rt Positive Sample PMA, LPS and BFA treated THP 1 cells, LPS treated RAW264. 7, mouse spleen, mouse